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Hit Identification and Hit-to-Lead |
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HD Biosciences provides services to our clients for their hit identification and hit-to-lead programs. We undertake assay development in major target classes, such as GPCRs, kinases, ion channels and transporters, and in a high-throughput screening format using plate-based platforms. Our screening capabilities span from cell line generation, biochemical, and cell-based functional assays for receptors, enzymes and ion channels in a |
variety of techniques, including: |
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Fluorescence (e.g. HTRF, FP, FRET, FLIPR, Flexstation) |
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Absorbance |
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Luminescence (e.g. luciferase, b-lactamase, deGFP, reporter gene) |
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Radiometrics (e.g. SPA, MicroBeta, Filtration) |
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Electrophysiology (e.g. patch clamps) |
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ImageXpress (e.g. live cell image HCA/HCS) |
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