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TNBS-IBD |
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| Model: |
2,4,6-trinitrobenzene sulfonic acid (TNBS) induced IBD in SJL/J mice |
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| Animal: |
SJL/J mice |
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| Inducer: |
TNBS |
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| Study duration: |
one week (in life) |
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| Pathological features: |
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Colon ulceration |
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Transmural leukocyte infiltration, distorted crypt and bowel-wall thickning |
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CD4-mediated TH1 disease |
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| Suitability: |
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Efficay study against crohn's disease |
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| Parameter measures: |
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Body weight |
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Clinical score (stool consistence, occult bleeding) |
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Colon weight/colon length |
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Histo-pathology assessment |
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IHC |
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cytokine (ELISA or RT-qPCR, optional) |
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The Latest Generation of Auto Patch Clamp Platform Launched at HDB  |
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WuXi Biology/HD Biosciences Presented at Webinar of "New Technologies for Target Discovery and Validation" |
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HD Biosciences Merges with WuXi AppTec |
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