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Radiometric Assay
Assays for ,most of target classes and phenotypic function
Variety of assay format and technology using 3H, 14C, 32P, 33P, 35S and 125I
 
Viewlux capability supporting high throughput screening
Radiometric assays remain the most powerful tool for studying GPCRs, NRs, ion channels, enzymes as well as transporters. Compared with non-radiometric approaches, radioligand binding assays offer the best methods to evaluate compound affinity towards target proteins including GPCR and ion channels. Radiometric enzyme assays involving use of [33P]-γ-ATP give better sensitivity than widely used ADP-glow or other testing systems. The radiolabelled amino acids are being widely used for research study on some key
transporters.
Radiometric Facility
HDB's state-of-the-art radioactive assay facilitate is equipped with scintillation counters (MicroBeta and TopCount), cell harvesters (FilterMate), high speed centrifuge (Toshiba), liquid handlers and the high throughput Viewlux to meet the needs of assay development,
HTS campaign and weekly SAR screenings.
Isotopes We Work With
HDB could handle various isotopes including 3H, 14C, 32P, 33P, 35S and 125I. If the isotope you are interested is not on our list, HDB could make the new addition within 4 weeks. Importation channel is also well established to transfer radiometric materials from
commercial vendors or client locations.
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HD Biosciences (China) Co.,Ltd
590 Ruiqing Road
Zhangjiang East Campus, Pudong, Shanghai 201201,
P.R.China
Tel: +86 (21) 5116 3700
Fax: +86 (21) 5116 3766
info@hdbiosciences.com
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