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Protein-Protein Interaction |
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Molecular recognition and binding of proteins with high sensitivity and selectivity is of central importance to essentially all biomolecular processes in a living cell. Replication, transcription, translation, signal transduction, protein trafficking and protein degradation are all accomplished by meticulously regulated assembled protein complexes. HD Biosciences offers services covering assay development and high throughput screening to |
help you identify compounds targeting protein-protein interaction. |
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Assay Development |
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Assay formats: TR-FRET (HTRF, LANCE), AlphaScreen, fluorescence polarization, |
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Biacore, radiometric, etc. |
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Assay development includes routine assay optimization (protein titration, KD determination, identification of equilibrium time etc.) and assay validation (DMSO |
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tolerance, Z' test, compound validation, etc.). |
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KD determination for protein-protein interaction using TR-FRET based technology |
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Successful development of a HTRF based protein-protein interaction assay |
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Assay formats: TR-FRET (HTRF, LANCE), AlphaScreen, fluorescence polarization, radiometric, etc. |
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HTS validation includes uniformity test, pilot screening etc. |
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Capable of generating over 50,000 data points per day for most screenings |
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Data turnaround time: 1-2 weeks |
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The Latest Generation of Auto Patch Clamp Platform Launched at HDB  |
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WuXi Biology/HD Biosciences Presented at Webinar of "New Technologies for Target Discovery and Validation" |
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HD Biosciences Merges with WuXi AppTec |
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