HDB offers compound screening and profiling services to assist our clients for lead identification and optimization. We focus our efforts on lead selection and assessment to gear at providing clients with reliable and accurate information through scientific procedures. Panels of profiling assays including biochemical assays and cell-based functional assays (i.e. in various target classes such as GPCRs, enzymes, ion channels and transporters), in vitro ADMET assays and pathway-based cellular phenotypic assays as well as high-content assays offer an integrated tool for clients to better characterize and

Pharmacology profiling has become an invaluable tool for leadcompound selection, optimization and candidate prioritization. Analysis ofprofile data identifies off-target interactions that can help predict potential side-effects, efficacy and safety of compounds under development before theyprogress to the more costly stages of preclinical and clinical trials. HDBoffers comprehensive profiling services to fit our clients' drug discovery