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EAE-MOG
Model: MOG35-55 induced chronic EAE in C57BL/6 mice
Animal: C57BL/6
Immunogen: MOG35-55 Peptide
Study duration: 30 days (in life)
Pathological features:
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Chronic model
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Inflammatory Infiltration and de-myelination in CNS
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Antibody response involves in pathology development
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Large therapeutic window
Suitability:
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De-myelination,axon damage,neuron regeneration and antibody intervention
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Efficacy study
Parameter measures:
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Body weight
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clinical score
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Histo-pathological assessment
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Cytokine ELISA (optional)
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RT-qPCR (optional)
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IHC (optional)
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P.R.China
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