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DSS-IBD
Model: Dextran sulphate Sodium (DSS) induced colitis in mice
Animal: C57BL/6 mice
Inducer: DSS
Study duration: one week (in life)
Pathological features:
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Colon inflammation
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Crypt and epithelial cell damage with ulceration, tissue edema
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Activation of the innate immune system
Suitability:
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Study the innate immune system and epithelial barrier function
Parameter measures:
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Body weight
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Clinical score (stool consistence, occult bleeding)
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Colon weight/colon length
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Histo-pathology assessment
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IHC
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cytokine (ELISA or RT-qPCR, optional)
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Zhangjiang East Campus, Pudong, Shanghai 201201,
P.R.China
Tel: +86 (21) 5116 3700
Fax: +86 (21) 5116 3766
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