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Arthritis (AIA) |
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Model: |
Adjuvant induced arthritis in rats (AIA) |
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Animal: |
Lewis rat |
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Immunogen: |
modified CFA |
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Study duration: |
5 weeks (in life) |
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Pathological features: |
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Marked bone resorption and periosteal bone proliferation |
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T cell and neutrophil dependent, complement independent |
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Cartilage damage to a lesser degree |
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B cell invovlvement is minimal |
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Suitability: |
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COX inhibitor development, general anti-arthritis development |
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Parameter measures: |
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Body weight |
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clinical score |
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Hind paw swelling |
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X-ray examination |
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Histo-pathological examination |
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The Latest Generation of Auto Patch Clamp Platform Launched at HDB |
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WuXi Biology/HD Biosciences Presented at Webinar of "New Technologies for Target Discovery and Validation" |
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HD Biosciences Merges with WuXi AppTec |
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