Print E-mail Contact us
Arthritis (AIA)
Model: Adjuvant induced arthritis in rats (AIA)
Animal: Lewis rat
Immunogen: modified CFA
Study duration: 5 weeks (in life)
Pathological features:
-
Marked bone resorption and periosteal bone proliferation
-
T cell and neutrophil dependent, complement independent
-
Cartilage damage to a lesser degree
-
B cell invovlvement is minimal
Suitability:
-
COX inhibitor development, general anti-arthritis development
Parameter measures:
-
Body weight
-
clinical score
-
Hind paw swelling
-
X-ray examination
-
Histo-pathological examination
----------------------
----------------------
HD Biosciences (China) Co.,Ltd
590 Ruiqing Road
Zhangjiang East Campus, Pudong, Shanghai 201201,
P.R.China
Tel: +86 (21) 5116 3700
Fax: +86 (21) 5116 3766
info@hdbiosciences.com
SERVICES
|
THERAPEUTIC AREAS
|
NEWS & EVENTS