HD Biosciences' proprietary
technologies enable us to provide high-quality recombinant
cell lines for various functional assays and for high
throughput drug screening. Our cell lines with over
expressed G-protein coupled receptor, ion channels
or other drug targets provide solutions for drug discovery.
The functional assays can be transcriptional readout
(reporter gene assays) and/or intracellular calcium
flux detection for GPCRs, and membrane potential dyes
or calcium influx for certain ion channels. All HDB
cell lines have been well-characterized and show stability
in assays for at least 30 passages. (The
Sample of Cell Line Product Description).
All cell lines are available frozen at 2 x 106 cells/ml/vials and have been tested negative for mycoplasma.
Examples
of Agonist/Antagonist Responsive Curves for GPCR
Examples
of Agonist/Antagonist Responsive Curves for Ion
Channel
