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Animal Models for Infectious Diseases
Drug candidates with specific anti-pathogen activity can be better evaluated in animals which provide more complex physiological environment, the efficacy will be a combined reflection of pharmacokinetics and pharmacodynamics of the test compounds. HDB can provide services for in vivo drug screen and development against specific pathogen, which is supported by designated ABSL2 facility, certified BSL2 and 3 laboratories for in vitro bacteria and virus production, availability of pathogenic virus and bacteria strain, multiple
formats of assays and established infectious animal models.
Animal models available:
Supporting assays includes:
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Clostridium difficile infection model
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Colonization assay
Escherichia coli infection model
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Virus shedding
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Salmonella typhimurium infection
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Survival assay
model
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Histology/Pathophysiology assessment
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Influenza A/B infection model
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Genotyping and phenotyping assay
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Other models in development
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Immunology/biochemistry related
assays
Representative data from Clostridium difficile induced GI infection model
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HD Biosciences (China) Co.,Ltd
590 Ruiqing Road
Zhangjiang East Campus, Pudong, Shanghai 201201,
P.R.China
Tel: +86 (21) 5116 3700
Fax: +86 (21) 5116 3766
info@hdbiosciences.com
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